Renal toxicity refers to damage or injury to the kidneys due to the exposure of certain drugs, toxins, or chemicals. Potential causes of renal toxicity include prolonged use of medications like nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics, and chemotherapy drugs. Other risk factors include pre-existing kidney disease, age, and underlying medical conditions like diabetes or hypertension. Symptoms of renal toxicity may include decreased urine output, fluid retention, and swelling in the legs and ankles. Treatment may include discontinuing the offending medication or toxin and supportive care to help manage symptoms and prevent further damage to the kidneys.

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